tert-butyl 2 4-dioxopiperidine-1-carboxylate (CAS# 845267-78-9)

Qaanuunka molecular	C10H15NO4
Molar Mass	213.23
Cufnaanta	1.199
Boling Point	373.8± 35.0 °C (La saadaaliyay)
Barta Fiishka	179.9°C
Uumiga Uumiga	8.72E-06mmHg at 25°C
pKa	10.67±0.20 (La saadaaliyay)
Xaalada Kaydinta	Ku hay meel mugdi ah, ku xidhan meel engegan, heerkulka qolka
Tusmada Dib-u-celinta	1.493
MDL	MFCD10566071

Faahfaahinta Alaabta

Xeerarka Khatarta	20/21/22 - Waxyeelo xagga neefsashada, taabashada maqaarka iyo haddii la liqo.
Sharaxaada Badbaadada	S23 - Ha neefsan uumiga. S24/25 - Iska ilaali taabashada maqaarka iyo indhaha.
WGK Germany	3
Koodhka HS	29337900

Isticmaal	2, 4-dipiperidon-1-formate tert-butyl formate waa isku-dhafka phenoxymethyl-dihydrothiazolopyridone derivatives Reactants ee alaabta, sida qaab-dhismeedka qaab-dhismeedka togan ee xulashada (PAM) ee glutamate metabolized 5 (mGlu5).
codsi	2, 4-dioperidone-1-tert-butyl formate waxaa inta badan loo isticmaalaa sida dhexdhexaad ah organic iyo dhexdhexaad ah farmashiyaha, waxaana loo isticmaali karaa in shaybaarka cilmi-baarista iyo habka horumarinta iyo habka synthesis daawada kiimikada.
diyaarinta	tallaabo a: ku dar EDCI (191.7g) DMF (400mL) xal 3- (tert-butoxycarbonylamino) propionic acid (189.2g,1.0mol), meldamic acid (144.1g,1.0mol) iyo DMAP (135.0g,1.1mol) ) lagu qaboojiyey qubeyska barafka, 1.0mol). Dareen-celinta ka dhalatay ayaa la walaaqay habeenkii heerkulka qolka. Dareen-celinta waxaa lagu demiyay 200ml H2O. Isku darka ka dhashay waxaa lagu daray hoos u dhig H2O(2.0L) iyadoo la hoos marinayo mashiinka. Aadka la helay ayaa la sifeeyay oo si fiican loogu dhaqay biyo ilaa pH 7 si loo helo badeecada (283g,90% dhalidda). Tallaabada B: Xalka 3- (2, 2-dimethyl-4, 6-dioxo-1, 3-dioxan-5-yl) -3-oxopropylcarbamate tert-butyl ester (100g,317.46mmol) ee toluene (1500mL) waxaa lagu kululeeyaa 100 ° C ilaa 4 saacadood. Dareen-celinta waxa lagu qaboojiyaa heerkulka qolka waxaana la saaray cadaadis la dhimay si loo helo badeeco ceeriin ah. Alaabta (56g,83% dhalidda) waxaa lagu sifeeyay MTBE-shiidid.