Sodium nitroprusside dihydrate (CAS# 13755-38-9)

Hantida Kiimikada:

Qaanuunka molecular	C5H4FeN6Na2O3
Molar Mass	297.95
Cufnaanta	1.72
Biyuhu milmayn	Biyo ku milmay. ethanol yara milma.
Solubility	Ku milmay biyaha (400 g/l) at 20 °C, iyo ethanol (wax yar milmi).
Muuqashada	Karistaanka cas ee qoto dheer
Cufis-jiidad gaar ah	1.72
Midabka	Casaan Ruby
Xadka Muujinta	ACGIH: TWA 1 mg/m3NIOSH: IDLH 25 mg/m3; TWA 1 mg/m3
Merck	14,8649
PH	5 (50g/l, H2O, 20℃)
Xaalada Kaydinta	2-8°C
Xasaasi ah	Hygroscopic
MDL	MFCD00149192
Tilmaamaha Jirka iyo Kiimikada	Budada crystalline cas-brown, aan ur lahayn; Dhadhan la'aan.
Isticmaal	Waxaa loo isticmaalaa sida reagent go'aaminta aldehydes, acetone, sulfur dioxide, zinc, biraha alkali, sulfides, iwm.
Barashada in vitro	Sodium Nitroprusside waa vasodilator waxtar leh. Sodium nitroprusside waxay leedahay saameyn vasodilatory ah oo wax ku ool ah ee arterioles iyo venules. Sodium Nitroprusside waxay jebisaa wareegga si ay u sii deyso nitric oxide (MAYA). MAYA waxay kicisaa cyclase guanylate muruqa siman ee xididdada dhiigga waxayna kordhisaa wax soo saarka cGMP intracellular. Tani waxay ugu dambeyntii keentaa nasinta murqaha siman ee xididdada dhiigga, kaas oo ballaadhiyaa xididdada dhiigga. Sodium nitroprusside waxay yaraynaysaa badinta murqaha siman ee xididdada dhiigga.
In vivo waxbarasho	Sodium nitroprusside (5 mg/kg) sida ku-deeqaha nitric oxide ayaa si weyn hoos ugu dhigay dhaawaca ischemia-ka-soo-celinta xiidmaha ee jiirka.

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Khatarta iyo Badbaadada

Xeerarka Khatarta	R25 - Sun ah haddii la liqo R26/27/28 - Aad u sun ah neefsashada, taabashada maqaarka iyo haddii la liqo.
Sharaxaada Badbaadada	S45 - Haddii ay dhacdo shil ama haddii aad dareento xanuun, raadso talo caafimaad isla markiiba (tus calaamadda mar kasta oo ay suurtagal tahay.) S36/37/39 - Xidho dhar ilaalin ku haboon, galoofyada iyo ilaalinta indhaha/wejiga. S22 - Ha neefsan boorka.
Aqoonsiga UN-ka	UN 3288 6.1/PG 3
WGK Germany	3
RTECS	LJ8925000
FLUKA BRAND F CODES	3
TSCA	Haa
Koodhka HS	28372000
Heerka khatarta	6.1
Kooxda Baakadaha	III
Sunta	LD50 afka Bakaylaha: 99 mg/kg

13755-38-9 - Tixraac

Tixraac

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1. Tian, Ya-qin, iyo al. "Isbarbardhigga farsamooyinka soo saarista kala duwan iyo hagaajinta ka-baxa microwave-ka caawiyay ...

13755-38-9 - Hordhac

Biyo ku milmay, wax yar ku milmay khamriga. Xalkeeda aqueous waa mid aan degganayn oo si tartiib tartiib ah u qudhmi kara oo cagaar noqon kara.

13755-38-9 - Macluumaadka Tixraaca

hordhac	sodium nitroprusside (qaabka molecular: Na2 [Fe(CN)5NO] · 2H2O, magaca kiimikaad: sodium nitroferricyanide dihydrate) waa vasodilator dhaq-dhaqaaq degdeg ah oo gaaban, kaas oo kiliinik ahaan loo isticmaalo hypertension degdeg ah sida qalalaasaha hypertensive, hypertensive encephalopathy, hypertension malignant, hypertension paroxysmal ka hor iyo ka dib qalliinka pheochromocytoma, iwm, waxa kale oo loo isticmaali karaa hypotension la xakameeyey inta lagu jiro suuxinta qaliinka.
saamayn	sodium nitroprusside waa vasodilator dhaqsaha badan oo awood leh, kaas oo si toos ah u saameeya muruqa siman ee halbowlaha iyo xididdada dhiigga, wuxuuna yareeyaa iska caabbinta xididdada durugsan iyadoo la ballaarinayo xididdada dhiigga., Soo saar saameyn antihypertensive. Kala-badhsiinta xididku waxa kale oo ay yarayn kartaa culayska ka hor iyo ka dib wadnaha, waxa ay wanaajisaa wax soo saarka wadnaha, waxa aanay hoos u dhigi kartaa reflux-dhiigga marka aanu waalka xidhin, si calamadaha wadna xanuunka shaqada looga nafiso.
tilmaamo	1. waxaa loo isticmaalaa hypotension degdeg ah ee xaaladaha degdega ah ee hypertensive, sida qalalaasaha hypertensive, hypertensive encephalopathy, hypertension malignant, hypertension paroxysmal ka hor iyo ka dib qalliinka pheochromocytoma, iyo sidoo kale waxaa loo isticmaali karaa hypotension la xakameeyey inta lagu jiro suuxinta qaliinka. 2. Wadna xanuunka degdega ah, oo ay ku jiraan bararka sambabada oo degdeg ah. Waxa kale oo loo isticmaalaa wadne-gabka degdega ah ee wadnaxanuun myocardial aadka u daran ama marka waalka (mitral ama aortic valve) aan la xidhin.
farmashiyaha	isla markiiba gaadha heerka ugu sarreeya ee dhiigga ka dib faleebooyinka xididka, heerkeeduna wuxuu ku xiran yahay qiyaasta. Badeecadan waxaa metabolized by unugyada dhiigga cas galay cyanide, cyanide ee beerka ayaa metabolized galay thiocyanate, iyo dheef-shiid kiimikaad ma laha dhaqdhaqaaq vasodilating; cyanide sidoo kale waxay ka qayb qaadan kartaa dheef-shiid kiimikaadka fitamiin B12. Alaabtani waxay shaqeysaa ku dhawaad isla markiiba ka dib maamulka waxayna gaartaa heerka ugu sarreeya ee ficilka, waxayna ilaalisaa 1 ~ 10 daqiiqo ka dib marka ay istaagto faleebo xididada. Nolosha kala bar ee bukaanada leh shaqada caadiga ah ee kelyaha waa 7 maalmood (oo lagu qiyaaso thiocyanate), oo la dheereeyo marka shaqada kelyaha ay liidato ama soodhiyamka dhiiggu aad u hooseeyo, waxaana ka soo baxa kelyaha.
Habka synthetic ee diyaarinta	sodium nitroprusside, oo ay ku jiraan tallaabooyinkan soo socda: 1) Isku-darka nitroso ferrocyanide copper: ku darida qadar ku habboon oo biyo nadiif ah si ay u milaan potassium nitroso-ferricyanide ee taangiga crystallization, kuleylinta ilaa 70-80 ℃ si buuxda u milaan, oo si tartiib ah ugu daraya copper sulfate pentahydrate xal aqueous dropwise, ka dib markii falcelinta lagu hayaa diirimaad 30 daqiiqo, centrifuge, ah Keega filter centrifuged (naxaas nitroso ferricyanide) ayaa la geliyey haanta crystallization. 2) Sodium nitroprusside synthetic (sodium nitronitroferricyanide): Diyaari xal aqueous sodium bicarbonate saturated sida waafaqsan saamiga quudinta, oo si tartiib ah hoos ugu riday nitroso ferricyanide at 30-60 degrees C. Ka dib falcelinta, centrifuge, ururiyaan sifaynta iyo lotion. 3) Xoog saarista iyo kirismaska: Sifaynta la ururiyey iyo kareemka waxaa lagu shubaa haanta fiirsashada faakuumka, iyo glacial acetic acid si tartiib ah ayaa loogu daraa hoos ilaa aan xumbo soo bixin. Daar bamka faakuumka oo kuleyl ilaa 40-60 darajo C, bilow feejignaanta, xooga saar tiro badan oo ah roobka kirismaska, xir waalka uumiga, vacuum valve si aad isugu diyaariso crystallization. 4) Qalajinta Centrifugal: crystallization ka dib, supernatant waa la saaraa, kiriimyada si siman ayaa loo walaaqay oo la gooyey, keega filter waxaa lagu dhejiyaa saxan bir ah oo aan lahayn, alaabtana waxaa lagu helaa qalajinta vacuum.
dhaqdhaqaaqa nafleyda	Sodium Nitroprusside waa vasodilator awood leh oo ka shaqeeya isagoo si iskiis ah u sii daaya MAYA ee dhiiga.
Bartilmaameedka	Qiimaha
Isticmaal	Loo isticmaalo sidii reagent go'aaminta aldehydes, ketones, sulfides, zinc, sulfur dioxide, iwm. Loo isticmaalo sida reagent go'aaminta aldehydes, acetone, sulfur dioxide, zinc, biraha Alkali, sulfide, iwm. Vasodilators. Xaqiijinta aldehydes iyo ketones, zinc, sulfur dioxide iyo sulfides birta alkali. Falanqaynta Chromatic, baaritaanka kaadida.