NN-Bis 9-fluorenylmethyloxycarbonyl-L-histidine CAS 98929-98-7

Sharaxaada Badbaadada	S22 - Ha neefsan boorka. S24/25 - Iska ilaali taabashada maqaarka iyo indhaha.
Koodhka HS	29242990

N(alpha),N(im) -di-fmoc-L-histidine(N(alpha),N(im)-di-fmoc-L-histidine -histidine. Qaabka kiimikaadkeedu waa C42H38N4O8 cufkeeda molecular waa 722.78g/mol.N(alpha),N(im)-di-fmoc-L-histidine waa unug ilaaliya asiidhyada amino waxaana si balaadhan loogu isticmaalaa isku-dhafka organic iyo falcelinta biochemical . Waxaa inta badan loo isticmaalaa in lagu habeeyo qaab-dhismeedka borotiinka iyo shaqada, iyo sidoo kale in la ballaariyo oo la wanaajiyo kala duwanaanshaha codsiga ee silsiladaha polypeptide. Xaruntan waxaa si weyn loogu isticmaalaa farsamooyinka isku-dhafka wajiga adag ee loogu talagalay wax ka beddelka N-terminus iyo hadhaaga histidine ee peptide iyo molecules borotiinka.

Habka diyaarinta N(alpha),N(im) -di-fmoc-L-histidine waxay inta badan ku lug leedahay saddex tallaabo. Marka hore, ethylene glycol dimethyl ether iyo diazotoluene ayaa lagu falceliyay iyada oo hoos timaada catalysis of cuprous chloride si loo farsameeyo 9-fluorenmethanol. Kadib, 9-fluorenecinol iyo L-histidine ayaa lagu falceliyaa xaaladaha acidic si loo helo N (alpha), N (im) -di-fmoc-L-histidine. Ugu dambeyntii, badeecada saafiga ah waxaa lagu helaa tillaabooyin crystallization iyo nadiifinta.

Marka la eego macluumaadka badbaadada, N (alpha), N(im)-Ma jiraan warbixino cilmi baaris oo badan oo khuseeya badbaadada gaarka ah ee di-fmoc-L-histidine, markaa taxaddar ayaa loo baahan yahay. Marka shaybaadhka lagu isticmaalo, waa in la qaadaa tillaabooyinka badbaadada ku habboon, oo ay ku jiraan xidhashada qalabka ilaalinta habboon, sida galoofyada shaybaadhka iyo muraayadaha, iyo ka fogaanshaha taabashada maqaarka iyo indhaha. Isla mar ahaantaana, waa in lagu kaydiyaa weel qallalan, hawo leh oo xiran, kana fog dabka iyo walxaha guban kara. Macluumaad faahfaahsan oo ammaan ah, waxaa lagu talinayaa inaad la tashato suugaanta ku habboon ama la tasho xirfadle.