N-Cbz-L-Leucine (CAS# 2018-66-8)
Khatarta iyo Badbaadada
| Calaamadaha halista | Xn – Waxyeelo |
| Xeerarka Khatarta | R10 - guban kara R20/22 - Waxyeelo u leh neefsashada iyo haddii la liqo. R37/38 - Ka xanaajiso habka neefsashada iyo maqaarka. R40 - Caddayn xaddidan ee saamaynta kansarka R41 - Khatarta dhaawaca daran ee indhaha R36/37/38 - Waxay ka xanaajisaa indhaha, habka neefsashada iyo maqaarka. R20/21/22 - Waxyeelo xagga neefsashada, taabashada maqaarka iyo haddii la liqo. R67 - Uumiga wuxuu keeni karaa lulmo iyo dawakhaad R63 - Khatarta suurtagalka ah ee waxyeellada ilmaha caloosha ku jira R19 - Waxa laga yaabaa inay sameeyaan peroxides qarxa |
| Sharaxaada Badbaadada | S16 - Ka fogow ilaha dabka. S26 - Haddii ay dhacdo in indhaha la taabto, isla markiiba ku raaci biyo badan oo raadso talo caafimaad. S36/37/39 - Xidho dhar ilaalin ku haboon, galoofyada iyo ilaalinta indhaha/wejiga. S45 - Haddii ay dhacdo shil ama haddii aad dareento xanuun, raadso talo caafimaad isla markiiba (tus calaamadda mar kasta oo ay suurtagal tahay.) S36 - Xidho dhar ilaalin ku habboon. S36/37 - Xidho dhar difaac ku haboon iyo galoofyada. S60 - Maaddadan iyo weelkeeda waa in lagu tuuraa sida qashinka khatarta ah. |
| Aqoonsiga UN-ka | UN 1993 3/PG 3 |
| WGK Germany | 3 |
| RTECS | OH2921000 |
| Koodhka HS | 29242990 |
N-Cbz-L-Leucine (CAS# 2018-66-8) horudhac
Cbz-L-leucine, magaca buuxa ee Boc-L-leucine (Boc waxay u taagan tahay kooxda ilaalinta dibutoxycarbonyl), waa soosaar amino acid ah. Kuwa soo socdaa waa hordhac dabeecadeeda, isticmaalkeeda, hababka wax-soo-saarka iyo macluumaadka badbaadada:
Tayada:
- Muuqashada: Caddaan crystalline adag
-Ku milmi: Ku milma ethanol, dimethylformamide (DMF) iyo dichloromethane
Isticmaal:
- CBZ-L-Leucine waa koox ilaalinta amino acid caadi ahaan loo isticmaalo oo ilaalisa kooxda hydroxyl ee leucine inta lagu jiro isku-darka peptides si looga hortago in ay la falgasho fal-celiyeyaasha kale. Isku-dhafka peptide halkaasoo hadhaaga leucine badan loo baahan yahay in la soo bandhigo, Cbz-L-leucine ayaa loo isticmaali karaa si loo ilaaliyo kooxda hydroxyl ee leucine ee hababka soo-saarka xiga.
- Leucine waa amino acid muhiim ah oo door muhiim ah ka ciyaara qaab dhismeedka borotiinka iyo shaqada.
Habka:
- Diyaarinta Cbz-L-leucine guud ahaan waxaa lagu helaa falcelinta leucine ee Boc-OSu (Boc-N-nitrocarbonyl-L-leucine). Dareen-celinta, Boc-OSu waxay u shaqeysaa sidii soo-bandhige kooxda ilaalinta waxayna ku martaa falcelinta esterification leucine si ay u dhaliso Cbz-L-leucine.
Macluumaadka Badbaadada:
- Cbz-L-leucine waa kiimiko waana in si fiican loo kaydiyaa meel ka fog dabka iyo oxidants.
- Inta lagu jiro isticmaalka, ka fogow inaad neefsato boodhkeeda ama aad la kulanto maqaarka iyo indhaha.
Raac dhaqamada nabdoon ee khuseeya marka aad wax ka qabanayso oo aad kaydinayso, oo xidho qalabka ilaalinta shakhsi ahaaneed ee habboon sida galoofyada shaybaadhka iyo ilaalinta indhaha.
