Methoxymethyl triphenylphosphonium chloride (CAS# 4009-98-7)

Adeegsada

(Methoxymethyl) chloride triphenylphosphorus waxaa loo isticmaalaa in lagu farsameeyo cefaltacin, taas oo ah daawada fayraska iyo ka hortagga burooyinka. Waxa kale oo loo isticmaalaa in lagu farsameeyo qayb ka mid ah paclitaxel.

Diyaarinta

Habka loogu talagalay synthesizing (methoxymethyl) triphenylphosphorus chloride, oo ka kooban tallaabooyinka soo socda: iyadoo la ilaalinayo nitrogen, lagu daro 50mL of acetone anhydrous ee reactor, ka dibna lagu daro 32g of triphenylphosphine, walaaqaya iyo kor u qaadida heerkulka ilaa 37 ° C, ilaalinta heerkulka joogtada ah. , ku darida 20g oo methyl chloromethyl ether ah reactor-ka, ka dibna ka falcelinaya 37 ° C ee 3h, si tartiib tartiib ah kor ugu qaadaya heerkulka 47 ° C ee heerka 1 ° C / min, falcelinta ayaa la sii waday 3h, falcelinta waa la joojiyay, iyo 37.0g (methoxymethyl) chloride triphenylphosphorus waxaa lagu helay sifeynta, anhydric dhaqidda etherka iyo qalajinta oo leh wax-soo-saarka 88.5%.