Lomefloxacin hydrochloride CAS 98079-52-8
Khatarta iyo Badbaadada
Calaamadaha halista | Xn – Waxyeelo |
Xeerarka Khatarta | 22 – Waxyeelo haddii la liqo |
WGK Germany | 3 |
RTECS | VB1997500 |
Koodhka HS | 29339900 |
Go'aaminta nuxurka
Xogta La Xaqiijiyay
lagu cabiray waxqabadka sare ee chromatography dareeraha (Guud 0512).
xaaladaha chromatographic iyo imtixaanka ku habboonaanta nidaamka
jel silica oo ku xidhan octylsilane sida buuxinta; Sodium pentanesulfonate xal (sodium pentanesulfonate 1.5g, ammonium dihydrogen phosphate 3.0g, biyo 950ml si ay u milaan, hagaajin pH in phosphoric acid, milo ilaa 1000ml biyo) -Methanol (65:35) sida wareega wareega, heerka socodka 1.2ml per daqiiqo, dhererka mowjadda ogaanshaha ee 287mn. Qaado nidaamka xalka lagu dabaqi karo 20u1 hoosta shayga walxaha la xidhiidha oo ku dur Chromatograph dareeraha bini'aadamka. Waqtiga haynta lomefloxacin waa qiyaastii 9 daqiiqo, heerka kala soocida udhaxeysa ugu sarreysa wasakhda waqtiga qaraabada ah ee ku saabsan 0.8 iyo heerka ugu sarreeya ee lomefloxacin waa inuu ka weynaadaa 2.0, xallinta inta u dhaxaysa ugu sarreysa lomefloxacin iyo heerka ugu sarreeya ee wasakhda waqtiga qaraabada 1.1 waa in buuxi shuruudaha.
qiyaasid
Qaado qaddarka saxda ah ee alaabtan, miisaan sax ah, oo lagu daray kala dirida wajiga wareega iyo milanka tirada ee lagu sameeyay lm kasta oo ka kooban qiyaastii 0. Xalka lmg waxa loo adeegsaday xalinta tijaabada, 20ul waxa lagu duray chromatograph-ka dareeraha ah si sax ah, iyo chromatogram-ka ayaa la duubay. Walax kale oo tixraac ah lomefloxacin ayaa la qaatay oo lagu go'aamiyay hab la mid ah. Waxa ku jira lomefloxacin (C17H19F2N303) ee muunada waxaa lagu xisaabiyay aagga ugu sarreeya iyadoo loo eegayo habka caadiga ah ee dibadda.