Fmoc-L-glutamic acid-gamma-benzyl ester (CAS# 123639-61-2)

Fluorene methoxycarbonyl-L-glutamic acid-Γ-benzyl waa unug dabiici ah oo loo isticmaalo isku-dhafka peptide-ka ee isku-dhafka wejiga adag. Dabeecaddeeda:
- Muuqashada: Cadaan ilaa cirro huruud ah oo adag
- Solubility: Fmoc-L-Glu(OtBu) -OH waxay leedahay milmi wanaagsan oo ka dhex jira dareerayaasha dabiiciga ah ee caadiga ah.

Isticmaalka ugu muhiimsan ee Fmoc-L-Glu (OtBu) -OH waa koox ilaalin ah oo ku jirta isku-dhafka peptide. Marka la abuurayo silsiladaha peptide, Fmoc-L-Glu (OtBu) -OH waxay ku xidhan tahay asiidhyada amino, iyaga oo ka ilaalinaya waxqabadkooda fal-celin aan gaar ahayn oo leh fal-celin kale. Ka dib marka falcelinta la dhammeeyo, Fmoc-L-Glu(OtBu) -OH waa laga saari karaa iyadoo meesha laga saarayo kooxda ilaalinta si loo soo celiyo waxqabadka amino acids.

Diyaarinta Fmoc-L-Glu(OtBu) -OH waa mid aad u adag oo guud ahaan waxay u baahan tahay isticmaalka taxane ah oo ka mid ah tillaabooyinka isku dhafka dabiiciga ah. Glutamic acid waxaa lagu falceliyaa bromoacetate si loo helo ethyl glutamate. Ka dib, ethyl glutamate waxaa lagu falceliyaa alkolada benzyl si loo sameeyo ethyl glutamate benzyl alkohol ester. Ethyl glutamate benzyl alkohol ester ayaa lagu falceliyay Fmoc-Cl si loo dhaliyo badeecada la beegsanayo Fmoc-L-Glu(OtBu) -OH.

Macluumaadka Badbaadada: Fmoc-L-Glu(OtBu) -OH waa daawo shaybaar waxayna u baahan tahay in lagu isticmaalo hawlgal shaybaar oo badbaado leh. Raac hab-dhaqannada badbaadada shaybaadhka guud, oo ay ku jiraan xidhashada qalabka ilaalinta shakhsi ahaaneed (tusaale, galoofyada shaybaadhka, muraayadaha indhaha, iwm.), ka fogaanshaha maqaarka maqaarka iyo neefsashada, iyo ka shaqaynta shaybaar hawo fiican leh. Xarunta waa in lagu kaydiyaa weel hawo-mareen, oo ka fog dabka iyo oxidants.