Fmoc-L-Glutamic acid 1-tert-butyl ester (CAS# 84793-07-7)

Hordhac

Fluorene methoxycarbonyl-L-glutamate-1-tert-butyl ester, oo sidoo kale loo yaqaan Fmoc-L-glutamic acid-1-tert-butyl ester, waa unug dabiici ah oo caadi ahaan loo isticmaalo isku-dhafka peptide-ka iyo isku-dhafka adag ee wejiga dabiiciga ah.

Tayada:

Fluorene methoxycarbonyl-L-glutamic acid-1-tert-butyl waa mid adag oo leh kiristaalo cad ilaa huruud ah. Waxay leedahay milmayn hoose oo biyaha ah laakiin milmayn wanaagsan ayaa ku jirta dareerayaasha organic sida dimethyl sulfoxide ama methanol.

Isticmaal:

Fluorene methoxycarbonyl-L-glutamic acid-1-tert-butyl waa amino acid inta badan loo isticmaalo ilaalinta peptide synthesis. Waxaa loo isticmaali karaa in lagu ilaaliyo kooxda iyada oo loo marayo falcelinta, si ay u soo bandhigto isku-dhafka iyo kordhinta silsiladda peptide dheeraad ah. Xaruntani waxay si gaar ah ugu habboon tahay isku-dhafka wejiga adag, halkaasoo silsiladaha peptide ay ku xiran yihiin asiidhyada amino-ka ilaalinta ee laamaha resin.

Habka:

Diyaarinta fluorene methoxycarbonyl-L-glutamic acid-1-tert-butyl waxaa inta badan lagu gaaraa isku-dhafka kiimikada. Fluorene methanol marka hore waxa lagu dhex abuuraa fluorene karboxyl chloride iyada oo loo marayo fal-celin kiimikaad, ka dibna waxa lala falgalaa L-glutamic acid si uu u sameeyo fluorene methoxycarbonyl-L-glutamic acid, ugu danbayna waxa uu la falgalaa tert-butanol si uu u sameeyo wax soo saarka ugu dambeeya.

Macluumaadka Badbaadada:

Fluorene methoxycarbonyl-L-glutamic acid-1-tert-butyl waxaa guud ahaan loo arkaa inaysan lahayn wax sun ah oo cad oo bini'aadamka ah oo ku jira xaaladaha tijaabada ah ee caadiga ah. Hab-maamuuska badbaadada shaybaadhka ee khuseeya waxa loo baahan yahay in la raaco marka la maaraynayo, oo ay ku jiraan xidhashada galoofyada ilaalinta iyo muraayadaha, iyo ku shaqaynta xaaladaha hawo fiican leh.