Fmoc-L-2-Aminobutyric acid (CAS# 135112-27-5)
Khatarta iyo Badbaadada
| Sharaxaada Badbaadada | S22 - Ha neefsan boorka. S24/25 - Iska ilaali taabashada maqaarka iyo indhaha. |
| WGK Germany | 3 |
| Koodhka HS | 2924 29 70 |
| Heerka khatarta | XANUUNSAN |
Fmoc-L-2-Aminobutyric acid (CAS# 135112-27-5)hordhac
L-2- (fluorenylmethoxycarbonylamino) butyric acid, oo sidoo kale loo yaqaan Fmoc-glutamic acid (L-2- (9-fluorenylmethoxycarbonylamino) butyric acid), waa walax dabiici ah. Kuwa soo socdaa waa sharaxaadda qaar ka mid ah hantideeda, adeegsigeeda, hababka iyo macluumaadka badbaadada:
Dabeecadda:
-Muuqaalka: Budada crystalline aan midab lahayn ama wax yar huruud ah;
-Qaabka molecular: C26H23NO4;
-Miisaanka molecular: 413.47g/mol;
- dhibic dhalaalaysa: qiyaastii 166-168 ℃;
-Solubility: Fmoc-glutamic acid waxay ku milmi kartaa dareerayaasha organic sida dimethylformamide iyo hydrofluoric acid.
Isticmaal:
Fmoc-glutamic acid, oo ah koox ilaalin ah, ayaa inta badan loo isticmaalaa isku-dhafka peptide, gaar ahaan isku-darka isku-dhafka peptide-ka xasilloon iyo isku-darka peptides Levenstein (Levenshtein peptide). Waxaa loo isticmaali karaa sida dhexdhexaadiyaha synthetic ee acids amino, ama loo isticmaalo isku-dhafka wajiga adag, chromatography dareeraha waxqabadka sare, iwm.
Habka Diyaarinta:
Diyaarinta Fmoc-glutamic acid guud ahaan waxaa ka mid ah tillaabooyinka soo socda:
1. Nidaamka anhydrous, L-glutamic acid waxaa lagu falceliyaa Fmoc-OSu (fluorenylmethoxycarbonyl-chloro anhydride), iyo sodium chloride (NaCl) ayaa loo isticmaalaa si kor loogu qaado falcelinta si loo dhaliyo Fmoc-glutamic acid Fmoc-A cusbada.
2. Milixda Fmoc-glutamic acid, waxay ku milmaysaa dareeraha (sida dimethylformamide) waxaana la mariyaa habka nadiifinta habboon (sida crystallization) si loo helo Fmoc-glutamic acid.
Macluumaadka Badbaadada:
Fmoc-glutamic acid guud ahaan waa mid xasiloon oo sun yar marka loo eego hawlgalka caadiga ah. Laakiin sida isku-darka organic, wali waxay u baahan tahay inaad fiiro gaar ah u yeelato tallaabooyinka amniga ee soo socda:
-Iska ilaali siigada oo la neefsado, taabashada maqaarka iyo indhaha;
Inta lagu jiro hawlgalka, xidho galoofyada ilaalinta, muraayadaha iyo dharka ilaalinta ee buuxiya shuruudaha badbaadada;
-Ka shaqee deegaan hawo leh si aad uga fogaato soo-gaadhista tooska ah muddo dheer;
-Haddii la rabo in la tuuro qashinka xaruntan, waa in si habboon loo qubeeyaa si waafaqsan xeerarka deegaanka.
Dabeecadda:
-Muuqaalka: Budada crystalline aan midab lahayn ama wax yar huruud ah;
-Qaabka molecular: C26H23NO4;
-Miisaanka molecular: 413.47g/mol;
- dhibic dhalaalaysa: qiyaastii 166-168 ℃;
-Solubility: Fmoc-glutamic acid waxay ku milmi kartaa dareerayaasha organic sida dimethylformamide iyo hydrofluoric acid.
Isticmaal:
Fmoc-glutamic acid, oo ah koox ilaalin ah, ayaa inta badan loo isticmaalaa isku-dhafka peptide, gaar ahaan isku-darka isku-dhafka peptide-ka xasilloon iyo isku-darka peptides Levenstein (Levenshtein peptide). Waxaa loo isticmaali karaa sida dhexdhexaadiyaha synthetic ee acids amino, ama loo isticmaalo isku-dhafka wajiga adag, chromatography dareeraha waxqabadka sare, iwm.
Habka Diyaarinta:
Diyaarinta Fmoc-glutamic acid guud ahaan waxaa ka mid ah tillaabooyinka soo socda:
1. Nidaamka anhydrous, L-glutamic acid waxaa lagu falceliyaa Fmoc-OSu (fluorenylmethoxycarbonyl-chloro anhydride), iyo sodium chloride (NaCl) ayaa loo isticmaalaa si kor loogu qaado falcelinta si loo dhaliyo Fmoc-glutamic acid Fmoc-A cusbada.
2. Milixda Fmoc-glutamic acid, waxay ku milmaysaa dareeraha (sida dimethylformamide) waxaana la mariyaa habka nadiifinta habboon (sida crystallization) si loo helo Fmoc-glutamic acid.
Macluumaadka Badbaadada:
Fmoc-glutamic acid guud ahaan waa mid xasiloon oo sun yar marka loo eego hawlgalka caadiga ah. Laakiin sida isku-darka organic, wali waxay u baahan tahay inaad fiiro gaar ah u yeelato tallaabooyinka amniga ee soo socda:
-Iska ilaali siigada oo la neefsado, taabashada maqaarka iyo indhaha;
Inta lagu jiro hawlgalka, xidho galoofyada ilaalinta, muraayadaha iyo dharka ilaalinta ee buuxiya shuruudaha badbaadada;
-Ka shaqee deegaan hawo leh si aad uga fogaato soo-gaadhista tooska ah muddo dheer;
-Haddii la rabo in la tuuro qashinka xaruntan, waa in si habboon loo qubeeyaa si waafaqsan xeerarka deegaanka.
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