Fmoc-D-3-Cyclohexyl Alanine (CAS# 144701-25-7)
Khatarta iyo Badbaadada
| Sharaxaada Badbaadada | S22 - Ha neefsan boorka. S24/25 - Iska ilaali taabashada maqaarka iyo indhaha. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10 |
| Koodhka HS | 2924 29 70 |
| Heerka khatarta | XANUUNSAN |
Hordhac
Fmoc-D-3-Cyclohexyl Alanine (CAS # 144701-25-7), oo inta badan loogu yeero si fudud sida FMOC-D-amino acid, waa unug dabiici ah. Waxaa lagu helaa iyadoo lagu daro kooxda methoxycarbonyl ee kooxda amino ee fmoc-3-cyclohexyl-D-alanine.
Marka laga hadlayo sifooyinka FMOC-D-amino acid, waa xal adag ama raad raac oo lagu milmi karo qaar ka mid ah dareerayaasha organic, sida dimethyl sulfoxide (DMSO) iyo methanol (MeOH). Waxay leedahay sifooyin nuugista UV oo xooggan, taasoo muujinaysa nuugista ugu badan ee inta u dhaxaysa 240-245 nm.
FMOC-D-amino acid waxay leedahay codsiyo badan oo kala duwan oo ku saabsan cilmi-baarista biochemical. Mid ka mid ah isticmaalka ugu caansan waa koox ilaalin ah oo loogu talagalay peptides synthetase-ka adag iyo polypeptides, ilaalinta hydroxyl ama kooxaha amino inta lagu jiro isku-dhafka. Intaa waxaa dheer, waxaa sidoo kale loo isticmaali karaa isku-darka xeryahooda steroid-ka noolaha ah iyo diyaarinta peptides ama borotiinnada taxane gaar ah.
Habka caadiga ah ee diyaarinta FMOC-D-amino acid waa in lagu daro reagent FMOC chlorinating kooxda amino ee fmoc-3-cyclohexyl-D-alanine, oo lagu sameeyo falcelinta xaalad dareere iyo falcelin habboon. Intaa ka dib, badeecada la rabo waxaa lagu heli karaa tillaabooyinka nadiifinta ku habboon sida soo saarista dareeraha iyo chromatography column.
Marka la eego macluumaadka nabdoonaanta, FMOC-D-amino acids aad bay ammaan ugu yihiin xaaladaha hawlgalka guud. Si kastaba ha ahaatee, weli waa lagama maarmaan in la qaado tallaabooyinka badbaadada shaybaadhka, sida xidhashada qalabka ilaalinta shakhsi ahaaneed ee habboon iyo ka shaqaynta jawi shaybaar oo hawo wanaagsan leh. Intaa waxaa dheer, iyadoo la raacayo shuruudaha gaarka ah ee shaybaadh kasta, nidaamyada hawlgalka badbaadada ee khuseeya iyo taxaddarrada waa in la raaco inta lagu jiro isticmaalka iyo maaraynta.
Marka laga hadlayo sifooyinka FMOC-D-amino acid, waa xal adag ama raad raac oo lagu milmi karo qaar ka mid ah dareerayaasha organic, sida dimethyl sulfoxide (DMSO) iyo methanol (MeOH). Waxay leedahay sifooyin nuugista UV oo xooggan, taasoo muujinaysa nuugista ugu badan ee inta u dhaxaysa 240-245 nm.
FMOC-D-amino acid waxay leedahay codsiyo badan oo kala duwan oo ku saabsan cilmi-baarista biochemical. Mid ka mid ah isticmaalka ugu caansan waa koox ilaalin ah oo loogu talagalay peptides synthetase-ka adag iyo polypeptides, ilaalinta hydroxyl ama kooxaha amino inta lagu jiro isku-dhafka. Intaa waxaa dheer, waxaa sidoo kale loo isticmaali karaa isku-darka xeryahooda steroid-ka noolaha ah iyo diyaarinta peptides ama borotiinnada taxane gaar ah.
Habka caadiga ah ee diyaarinta FMOC-D-amino acid waa in lagu daro reagent FMOC chlorinating kooxda amino ee fmoc-3-cyclohexyl-D-alanine, oo lagu sameeyo falcelinta xaalad dareere iyo falcelin habboon. Intaa ka dib, badeecada la rabo waxaa lagu heli karaa tillaabooyinka nadiifinta ku habboon sida soo saarista dareeraha iyo chromatography column.
Marka la eego macluumaadka nabdoonaanta, FMOC-D-amino acids aad bay ammaan ugu yihiin xaaladaha hawlgalka guud. Si kastaba ha ahaatee, weli waa lagama maarmaan in la qaado tallaabooyinka badbaadada shaybaadhka, sida xidhashada qalabka ilaalinta shakhsi ahaaneed ee habboon iyo ka shaqaynta jawi shaybaar oo hawo wanaagsan leh. Intaa waxaa dheer, iyadoo la raacayo shuruudaha gaarka ah ee shaybaadh kasta, nidaamyada hawlgalka badbaadada ee khuseeya iyo taxaddarrada waa in la raaco inta lagu jiro isticmaalka iyo maaraynta.
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