D-1-N-Boc-prolinamide (CAS# 35150-07-3)
Calaamadaha halista | Xn – Waxyeelo |
Xeerarka Khatarta | 22 – Waxyeelo haddii la liqo |
Sharaxaada Badbaadada | 24/25 - Ka fogow taabashada maqaarka iyo indhaha. |
WGK Germany | 2 |
Hordhac
D-1-N-Boc-prolinamide (D-1-N-Boc-prolinamide) waa iskudhis organic ah oo leh sifooyinka soo socda:
1. Muuqashada: Caddaan crystalline adag.
2. formula kelli: C14H24N2O3.
3. Miisaanka unugyada: 268.35g/mol.
4. barta dhalaalka: qiyaastii 75-77 darajo Celsius.
5. Solubility: Ku milmay biyaha iyo qaar ka mid ah dareerayaasha organic, sida chloroform, ethanol iyo dimethyl sulfoxide.
Mid ka mid ah isticmaalka ugu muhiimsan ee D-1-N-Boc-prolinamide waa sida reagent chiral oo loogu talagalay isku-dhafka asymmetric ee isku-dhafka kiimikada organic. Waxaa loo isticmaali karaa sidii dhisme ee qalfoofka chiral si loogu soo bandhigo macluumaadka chiral iyada oo loo marayo xarunteeda chiral, si loo helo xeryahooda chiral. Intaa waxaa dheer, waxaa sidoo kale loo isticmaali karaa sidii dhexdhexaad ah ee isku dhafka daawooyinka, sunta cayayaanka iyo molecules bioactive.
Habka loo diyaariyo D-1-N-Boc-prolinamide inta badan waa in laga falceliyo N-Boc-L-proline oo leh tert-butyl chloroformate hoos yimaada xaaladaha alkaline si loo abuuro dhexdhexaad N-Boc-L-proline methyl ester, ka dibna kulaylka daaweynta si soo saar badeecada la beegsanayo.
Marka la eego macluumaadka badbaadada, daraasado sun ah oo faahfaahsan ayaa D-1-N-Boc-prolinamide ka maqan. Si kastaba ha ahaatee, guud ahaan, hawlgallada badbaadada shaybaadhka ee caadiga ah waa in la raaco, iyo tallaabooyinka ilaalinta sida galoofyada, muraayadaha iyo dharka ilaalinta waa in fiiro gaar ah loo yeesho marka la isticmaalayo. Intaa waxaa dheer, waa in lagu kaydiyaa weel xiran si looga fogaado xiriir la leh ogsijiinta iyo qoyaanka. Haddii si lama filaan ah loo neefsado ama la taabto maqaarka iyo indhaha, isla markiiba ku raaci biyo badan oo raadso gargaar caafimaad. Haddii qashinka la tuurayo, xeerarka deegaanka waa in la raaco. Way fiicantahay in la isticmaalo oo la maareeyo xarunta iyadoo uu hagayo qof khibrad u leh kimistariga.