BOC-L-Phenylglycine (CAS# 2900-27-8)

Hordhac

N-Boc-L-Phenylglycine waa unug dabiici ah oo lagu sameeyay samaynta isku xidhka kiimikada ee u dhexeeya kooxda amino (NH2) ee glycine iyo kooxda carboxyl (COOH) ee benzoic acid. Qaab dhismeedkeedu waxa uu ka kooban yahay koox difaac ah (Boc group), oo ah kooxda tert-butoxycarbonyl, taas oo loo isticmaalo in lagu ilaaliyo falcelinta kooxda amino.

N-Boc-L-phenylglycine waxay leedahay sifooyinka soo socda:

- Muuqashada: Caddaan crystalline adag

- Solubility: Ku milmay qaar ka mid ah dareerayaasha organic, sida dimethylformamide (DMF), dichloromethane, iwm.

N-Boc-L-phenylglycine waxaa caadi ahaan loo isticmaalaa fal-celin-tilaabo-badan-qaadka ee isku-dhafka organic, gaar ahaan isku-darka xeryahooda peptide. Kooxda ilaalinta Boc waxaa ilaalin kara xaalado aashito ah, si kooxda amino ay u noqoto mid falcelis ah kadibna ay sameeyaan falcelino xiga. N-Boc-L-phenylglycine sidoo kale waxaa loo isticmaali karaa sidii derivative dhismaha xarumaha chiral ee isku-dhafka peptide.

Diyaarinta N-Boc-L-phenylglycine waxaa inta badan lagu fuliyaa tallaabooyinka soo socda:

Glycine waxaa lagu nadiifiyaa benzoic acid si loo helo benzoic acid-glycinate ester.

Isticmaalka falcelinta lithium borotrimethyl ether (LiTMP), benzoic acid-glycinate ester ayaa la soo saaray oo la falgaliyay Boc-Cl (tert-butoxycarbonyl chloride) si loo helo N-Boc-L-phenylglycine.

- N-Boc-L-phenylglycine waxaa laga yaabaa inay ka xanaajiso indhaha, maqaarka, iyo mareenka neefsiga waana in laga fogaado inta lagu jiro isticmaalka.

- Qalabka ilaalinta shakhsi ahaaneed sida galoofyada shaybaadhka, muraayadaha badbaadada, iwm waa in la xidhaa inta lagu jiro hawlgalka.

- Waa in lagu sameeyaa jawi shaybaar oo hawo wanaagsan leh.

- Ka fogow xidhiidhka oksaydhiyeyaasha iyo asiidhyada xooggan marka aad kaydinayso.

- Haddii la liqo ama la nuugo, isla markiiba raadso daryeel caafimaad, keen weelka xarunta, oo u gudbi macluumaadka badbaadada lagama maarmaanka ah dhakhtarka.