Boc-L-Glutamic acid 1-benzyl ester (CAS# 30924-93-7)

Hordhac

Boc-L-Glutamic acid 1-benzyl ester (Boc-L-Glutamic acid 1-benzyl ester) waa iskudhis dabiici ah oo leh qaacido kiimiko ah C17H19NO6 iyo cufnaanta molecular ee 337.34. Waa adage cad, oo ku milma dareerayaasha organic sida ethanol, dimethylformamide iyo chloroform.

Boc-L-Glutamic acid 1-benzyl ester waxaa caadi ahaan loo isticmaalaa isku-dhafka peptide-ka. Waxaa loo isticmaali karaa sida wakiilka micellar ama kooxda ilaalinta si loo ilaaliyo kooxda amino acid si looga hortago falcelinta aan loo baahnayn ee falcelinta kiimikada, isla markaana waxay hagaajin kartaa dhalidda. Intaa waxaa dheer, waxaa sidoo kale loo isticmaali karaa isku-darka daawooyinka polypeptide iyo molecules bioactive ee la xidhiidha.

Habka loo diyaariyo Boc-L-Glutamic acid 1-benzyl ester guud ahaan waa in lagu soo bandhigo kooxda ilaalinta Boc ee kooxda amino ee glutamic acid, iyo in lagu sameeyo falcelinta esterification ee benzyl anhydride ester booskan. Dareen-celinta guud ahaan waxaa lagu fuliyaa dhexdhexaad ama xaalado asaasi ah waxayna badanaa u baahan tahay wakhti go'an si loo hubiyo dhamaystirka falcelinta. Alaabta la helay waxaa lagu sifeyn karaa crystallization ama tillaabooyin nadiifin dheeraad ah.

Marka la eego macluumaadka badbaadada, badbaadada gaarka ah ee Boc-L-Glutamic acid 1-benzyl ester waxay u baahan tahay cilmi-baadhis iyo qiimayn dheeraad ah. Si kastaba ha ahaatee, sida kiimiko ahaan, waxa laga yaabaa inay leedahay xanaaq iyo sun gaar ah. Nidaamyada shaybaadhka ku habboon waa in la raaco marka la xidhiidho ama la isticmaalayo, waana in la sameeyaa taxaddarrada badbaadada ku habboon, oo ay ku jiraan xidhashada qalabka ilaalinta shakhsi ahaaneed (tusaale, G., galoofyada shaybaadhka, muraayadaha shaybaadhka, iwm.). Inta lagu jiro isticmaalka ama qashin-qubka, qashinka waa in si habboon loo qubeeyaa si looga fogaado wasakhowga deegaanka.