Boc-L-aspartic acid 1-benzyl ester (CAS# 30925-18-9)
| Sharaxaada Badbaadada | 24/25 - Ka fogow taabashada maqaarka iyo indhaha. |
| WGK Germany | 3 |
| Koodhka HS | 29242990 |
Hordhac
Boc-Asp-OBzl (Boc-Asp-OBzl) waa xarun leh sifooyinka soo socda:
1. Muuqashada: Caddaan crystalline adag.
2. Qaaciddada molecular: C24H27N3O7.
3. Miisaanka unugyada: 469.49g/mol.
4. Barta dhalaalka: qiyaastii 130-134 ° C.
Boc-Asp-OBzl waxaa si weyn loogu isticmaalaa biochemistry iyo kiimiko organic synthetic, oo inta badan loo isticmaalo isku dhafka peptides, borotiinada iyo daawooyinka, iyadoo la isticmaalayo soo socda:
1. Peptide synthesis: Iyadoo qayb ka ah kooxda ilaalinta (kooxda ilaalinta Boc), kooxda amino ee ku jirta aspartic acid amino acid waa la ilaalin karaa.
2. Cilmi-baarista daroogada: loogu talagalay isku-darka daawooyinka peptide ee leh ka-hortagga-bararka, ka-hortagga buro-celinta iyo xakamaynta difaaca jirka.
3. Falcelinta Enzyme: Boc-Asp-OBzl waxa loo isticmaali karaa substrate-ka falcelinta enzyme catalyzed.
Habka diyaarinta Boc-Asp-OBzl waa sida soo socota:
Aspartic acid iyo benzoyl chloride ayaa la esterified si ay u sameeyaan tert-butoxycarbonyl-aspartic acid benzyl ester (Boc-Asp-OMe), kaas oo ka dib lagu falceliyay sodium hexoxide si loo helo dhexdhexaad ah qaab N-hexanoate ah. Ugu dambeyntii, waxay maraysaa falcelinta benzoylation si loo soo saaro Boc-Asp-OBzl.
U fiirso macluumaadka soo socda ee badbaadada markaad isticmaalayso Boc-Asp-OBzl:
1. Iskudhisku waxa uu jidhka bini’aadamka u keeni karaa xajiin iyo cuncun, waana in laga fogaado taabashada tooska ah ee maqaarka iyo indhaha.
2. Waa in la qaadaa tillaabooyinka ilaalinta shakhsi ahaaneed ee habboon inta lagu jiro hawlgalka, sida xidhashada galoofyada iyo muraayadaha.
3. Qallaji oo xidh inta lagu jiro kaydinta, kana ilaali dabka iyo oksidat-ka.
4. Markaad isticmaalayso oo aad gacanta ku hayso Boc-Asp-OBzl, fadlan raac nidaamka qalliinka shaybaadhka saxda ah iyo hawlgalka badbaadada leh.
Fadlan la soco in markaad isticmaalayso Boc-Asp-OBzl ama kiimikooyin kasta, waa inaad si adag u raacdaa tilmaamaha hawlgalka badbaadada, oo aad samayso ilaalinta shakhsi ahaaneed iyo qiimaynta khatarta iyadoo loo eegayo xaaladda dhabta ah.
