BOC-D-ASP(OBZL)-OH (CAS# 92828-64-3)

Hordhac

(3R) -4- (benzyloxy) -3-[(tert-butoxycarbonyl) amino] -4-oxobutanoic acid (magaca aan la door bidin) ((3R) -4- (benzyloxy) -3-[(tert-butoxycarbonyl) amino] -4-oxobutanoic acid) waa iskudhis organic ah kaas oo qaacidada kelli waa C16H21NO6.

Iskudhisku waa nooc ka mid ah aspartic acid oo leh sifooyinka soo socda:

-Muuqaalka waa budo crystalline cad;

-Xasilooni heerkulka qolka, laakiin wuxuu ku dumin doonaa heerkulka sare;

-Ku milmi kara dareerayaasha dabiiciga ah ee caadiga ah sida methanol, ethanol iyo dichloromethane.

(3R)-4-(benzyloxy)-3-[(tert-butoxycarbonyl)amino]-4-oxobutanoic acid (magaca aan la door bidin) waxa uu leeyahay codsiyo kala duwan oo dhanka daawada ah:

-Waxaa loo isticmaalaa sidii dhexdhexaad ah oo loogu talagalay isku dhafka polypeptides iyo xeryahooda leh hadhaaga aspartic acid ee borotiinnada;

-Waxa kale oo loo isticmaali karaa sida dhexdhexaadiyaha synthetic ee daroogada.

Shaybaarka, habka diyaarinta (3R) -4- (benzyloxy) -3 - [(tert-butoxycarbonyl) amino] -4-oxobutanoic acid (magaca aan la door bidin) guud ahaan waa iyadoo la falcelinayo kooxda carboxyl ee aspartic acid tert-butoxycarbonyl isocyanate, iyo soo bandhigida kooxaha benzyl ester iyada oo loo marayo falcelin ku habboon shaqada.

Marka la eego macluumaadka badbaadada, (3R) -4- (benzyloxy) -3 - [(tert-butoxycarbonyl) amino] -4-oxobutanoic acid (magaca aan la door bidin) waxay leedahay xaddidan sunta iyo xogta khatarta ah, markaa hawlgalkeeda badbaadada leh waa inuu raaco shaybaadhka caadiga ah. tilmaamaha badbaadada. Xiro qalabka ilaalinta shakhsi ahaaneed ee habboon sida muraayadaha, galoofyada iyo jaakadaha shaybaadhka marka la isticmaalayo ama la tacaalayo. Isla mar ahaantaana, si looga fogaado xiriirka ay la leedahay oksaydhiyeyaasha xooggan iyo kuwa guban kara.