4,6-Dihydroxypyrimidine (CAS#1193-24-4)

Soo bandhigida 4,6-Dihydroxypyrimidine (CAS No.1193-24-4), Iskudhis la taaban karo oo lama huraan ah oo ku jira saaxadda kimistariga dabiiciga ah iyo horumarinta dawooyinka. Kala soocida pyrimidine ee gaarka ah waxaa lagu gartaa labadeeda kooxood ee hydroxyl ee ku yaala boosaska 4 iyo 6, taas oo si weyn kor ugu qaadeysa falcelinta iyo codsiyada suurtagalka ah.

4,6-Dihydroxypyrimidine waxaa loo aqoonsan yahay doorkeeda dhexdhexaadka ah ee isku-dhafka molecules bioactive ee kala duwan. Sifooyinkeeda qaabdhismeedku waxay u oggolaanayaan inay ka qaybqaataan fal-celin kiimikaad oo kala duwan, taasoo ka dhigaysa dhisme qiimo leh oo loogu talagalay cilmi-baarayaasha iyo soo-saareyaasha warshadaha dawooyinka. Awoodda isku dhafka ah ee sameynta curaarta hydrogen iyo ku lug yeelashada beddelka nucleophilic waxay furaysaa dariiqyada horumarinta wakiilada daweynta cusub.

Waxa intaa dheer in ay utility synthetic, 4,6-Dihydroxypyrimidine ayaa soo jiidatay dareenka waxqabadyada bayooloji ee suurtogalka ah. Daraasadaha hordhaca ah waxay soo jeedinayaan in laga yaabo inay soo bandhigto sifooyinka antimicrobial iyo antifungal, iyada oo u dhiganta musharax u ah baaritaanka dheeraadka ah ee barnaamijyada daahfurka daroogada. Muuqaalkeeda sunta hoose iyo sifooyinka milanka ee wanaagsan ayaa ka dhigaya ikhtiyaar soo jiidasho leh oo loogu talagalay qaabab kala duwan oo qiyaas ah.

Nadiifinteena sareeysa ee 4,6-Dihydroxypyrimidine waxaa lagu soo saaraa cabirada xakamaynta tayada adag, iyadoo la hubinayo inay buuxiso heerarka adag ee looga baahan yahay cilmi baarista iyo codsiyada warshadaha. Waxaa lagu heli karaa tirooyin kala duwan, waxay ku habboon tahay shaybaarrada, xarumaha cilmi-baarista, iyo shirkadaha dawooyinka ee doonaya inay kor u qaadaan maktabadahooda kiimikada ama horumariyaan isku-dhisyo cusub.

Marka la soo koobo, 4,6-Dihydroxypyrimidine (CAS No.1193-24-4) waa xarun muhim ah oo isku xirta farqiga u dhexeeya cilmi-baarista aasaasiga ah iyo codsiyada la taaban karo ee horumarinta daroogada. Iyada oo leh sifooyinkeeda gaarka ah iyo suurtagalnimada codsiyada kala duwan, waa qasab inay lahaadaan farmashiste ama cilmi-baare kasta oo doonaya inuu hal-abuuro dhinaca kimistariga daawada. Ku baadh fursadaha 4,6-Dihydroxypyrimidine maanta!