2 4-Difluorobenzoic acid (CAS# 1583-58-0)

Codsiga

2, 4-difluorobenzoic acid waa daroogo muhiim ah iyo sunta cayayaanka dhexdhexaadka ah, sida 2, 4-difluorobenzoic acid waxaa inta badan loo isticmaalaa in lagu sameeyo dawooyinka antifungal fluconazole, voriconazole iyo daroogada sunta cayayaanka dhexdhexaadka ah 4-fluorosalicylic acid, dhexdhexaad ah daroogada 3, 5-difluoroaniline, iwm 2, 4-difluorobenzoic acid waxa kale oo loo isticmaali karaa crystal dareere ah alaabta, kuwaas oo leh faa'iidooyinka qiimaha sare iyo rajada wanaagsan ee suuqa.

Diyaarinta

Ku dar 2, 4-dinitrotoluene iyo biyo weelka falcelinta, ku hagaaji qiimaha pH ilaa 7, walaaq oo kulayl ilaa 75°C. Potassium permanganate, magnesium sulfate iyo kicinta wareejinta wajiga ayaa lagu daray qaybo. Ka dib markaad ku darto, sii wad inaad walaaqdo oo ka jawaab celiso heerkul joogto ah 3 saacadood. Sifee inta kulul oo ku dhaq keega filter biyo kulul. Isku dar sifaynta, acidify leh 35% hydrochloric acid ilaa pH 2-3, waxaa jira tiro badan oo ah roobab cad ka dib markii crystals si buuxda u da'ay, sifeeyay, dhaqday, recrystalized, iyo la qalajiyey si aad u hesho crystals cad sida 2,4-dinitrobenzoic acid . Saamiga 2, 4-dinitrotoluene ilaa potassium permanganate waa 2.4: 1. Wax-soo-saarka tallaabadan waa 90.7%.

ku dar N,N-dimethylphthalamide weelka falcelinta, kulaylka 100 ~ 110 ℃, preheat 0.5 ~ 1h. Ku dar qallalan foloraydh potassium oo anhydrous ah hoos walaaq oo ku hay heerkulka preheated ilaa 0.5-1h. Taas ka dib, 2, 4-dinitrobenzoic acid iyo hexyltrimethylammonium bromide ayaa si deg deg ah loogu daray weelka falcelinta hal mar, kulaylka ayaa la sii waday ilaa 120 ℃, heerkulka ayaa la ilaaliyay iyo falcelinta kicinta ayaa la sii waday. Ka dib 7 saacadood ee falcelinta reflux, dareeraha waxaa lagu soo celiyaa distillation, ka dibna dareeraha falcelinta waxaa lagu nadiifiyaa uumiga. Jajabka la ururiyey waa emulsion cad. Ka dib markii ay istaagaan muddo wakhti ah, jajabka bartilmaameedka saliidda ah ayaa asal ahaan hoos u dhacaya, dareeraha cad ee cad ee qaybta sare ayaa lagu shubay, saliiddana waa la qaboojiyey si ay u kiciso crystals cad si ay u hesho badeecad cayriin; badeecada ceyriinka ah ayaa dib loo sawiray, shaandhaynta nuugista, dhaqida, iyo qalajinta si loo helo kiristaalo cad oo ah 2,4-difluorobenzoic acid. Saamiga qadarka 2, 4-dinitrobenzoic acid ilaa fluoride potassium waa 2.7:1. Wax-soo-saarka tallaabadan waa 72.4%.

Hordhac
2,4-Difluorobenzoic acid waa unug dabiici ah. Kuwa soo socdaa waa hordhaca guryaha, isticmaalka, hababka diyaarinta iyo macluumaadka badbaadada ee 2,4-difluorobenzoic acid:

Tayada:
- muuqaalka: 2,4-Difluorobenzoic acid waa crystalline cad oo adag.
- Solubility: Waxay ku milmi kartaa dareerayaasha dabiiciga ah ee caadiga ah sida ethanol, methanol iyo methylene chloride.

Isticmaal:
- Qalabka indhaha: Waxa kale oo loo isticmaali karaa mid ka mid ah alaabta ceeriin ee loogu talagalay diyaarinta qalabka indhaha iyo filimada indhaha.
Codsiyada warshadaha: 2,4-difluorobenzoic acid waxaa loo isticmaali karaa warshadaha elektiroonigga ah, dahaarka iyo warshadaha balaastikada leh anti-corrosion, anti-oxidation iyo saamaynta anti-ultraviolet.

Habka:
- 2,4-Difluorobenzoic acid waxaa lagu heli karaa fluorination of hydrofluoric acid leh p-methylanisole.

Macluumaadka Badbaadada:
- Marka la qalayo, waa in laga fogaado boodhka si looga fogaado neefsashada iyo indhaha. Isla mar ahaantaana, xaaladaha hawo wanaagsan waa in la ilaaliyaa.
- Iska ilaali inaad la xiriirto walxaha oksaydhiyeyaasha ee xooggan ama asiidhyada xooggan si aad uga fogaato falcelinta khatarta ah