1-Phenyl-3,4-dihydroisoquinoline(CAS#52250-50-7)
1-Phenyl-3,4-dihydroisoquinoline(CAS#52250-50-7)
1-Phenyl-3,4-dihydroisoquinoline, CAS nambar 52250-50-7, ayaa muujiyay soo jiidasho gaar ah oo ku saabsan maadada kimisteriga iyo daawada.
Laga soo bilaabo nuxurka kiimikada, molecule-keedu si xariif ah ayaa loogu daraa unugyada qaabdhismeedka sida kooxda phenyl iyo dihydroisoquinoline giraanta, qaabkan gaarka ah ee isku xirka atomigu wuxuu dhisaa qaybinta daruuraha elektaroonigga ah ee gaarka ah, taas oo abuureysa dhaqdhaqaaqeeda kiimikada gaarka ah iyo xasilloonida. Muuqaal ahaan, waxaa sida caadiga ah loo soo bandhigaa sida adag oo leh qaab crystalline gaar ah, midabku inta badan waa caddaan ama caddaan, iyo qaab-dhismeedka crystal waa mid joogto ah oo nidaamsan, kaas oo ku habboon nadiifinta iyo nadiifinta iyada oo la adeegsanayo dib-u-celinta. Marka la eego milanka, waxay muujinaysaa isbeddel gaar ah ee dareerayaasha organic caadiga ah sida ethanol iyo acetone, laakiin milanka biyaha waa mid aad u hooseeya, kaas oo si dhow ula xiriira polarity ee molecule, iyo sidoo kale waxay bixisaa aasaas u ah doorashada hababka dareeraha ee kala-soocidda dambe iyo falcelinta isku-darka.
Marka la eego rajada R&D ee dawooyinka, waxay leedahay firfircooni bayooloji oo suurtagal ah. Qaab dhismeedka kiimikada ee alaabtu waxay la mid tahay qaar ka mid ah alaabooyinka dabiiciga ah ee farmaajo ahaan firfircoon, taasoo soo jeedinaysa inay yeelan karto bartilmaameedyo isku mid ah. Sahaminta hordhaca ah waxay soo jeedinaysaa in laga yaabo inay saameyn ku yeelato waddooyinka calaamadaha neerfaha, waxaana la filayaa inay ka qaybqaataan horumarinta daawooyinka cusub ee cudurada neerfayaasha, sida cudurka Alzheimers iyo cudurka Parkinson, iyadoo la xakameynayo gudbinta neurotransmitter ee aan caadiga ahayn iyo joojinta hyperapoptosis ee unugyada dareemayaasha. Isla mar ahaantaana, goobta ka hortagga burooyinka, kooxaha firfircoon ee qaab-dhismeedkeeda ayaa laga yaabaa inay farageliyaan faafitaanka, socdaalka iyo habka duulaanka unugyada burooyinka, furitaanka fikrado cusub oo loogu talagalay daaweynta kansarka, dabcan, kuwani weli waa hore. heerka cilmi baarista shaybaarka, waxaana weli jira shaqo badan oo cilmi baaris ah oo la sameeyo ka hor codsiga bukaan-socodka.
Marka laga eego aragtida isku-dhafka warshadaha, habka isku-darka kiimikada dabiiciga ah ee hadda jira ayaa inta badan lagu tiirsan yahay, laga bilaabo alaabta ceeriin ee fudud, iyada oo loo marayo fal-celin-tilaabo badan si loo dhiso qalfoofka kelli ee adag, geeddi-socodku wuxuu ku lug leeyahay baaskiil-wareejin, beddelaad, uumi iyo noocyada kale ee falcelinta dabiiciga ah ee dabiiciga ah. , Cilmi-baarayaashu waxay sii wadaan inay hagaajiyaan xaaladaha falcelinta, hagaajinta wax-soo-saarka, yaraynta kharashyada, si ay u daboolaan baahida dabagalka qoto-dheer ee cilmi-baarista iyo wax-soo-saarka ballaaran ee suurtogalka ah. Iyada oo isku-dhafka tignoolajiyada ee dhinacyada kala duwan, horumarka dhan walba ah ee 1-Phenyl-3,4-dihydroisoquinoline ayaa la filayaa in la dardargeliyo, lagu durayo dardar cusub caafimaadka aadanaha iyo horumarka sayniska iyo teknoolajiyada.
