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1-Boc-3-piperidone CAS 98977-36-7

Hanti Kiimiko:

Qaanuunka molecular C10H17NO3
Molar Mass 199.25
Cufnaanta 1.099±0.06 g/cm3 (La saadaaliyay)
Meesha dhalaalaysa 35-40 °C (Iftiin)
Boling Point 289.8± 33.0 °C (La saadaaliyay)
Barta Fiishka >230°F
Biyo La'aanta Waa mid aan lagu milmi karin biyaha.
Uumiga Uumiga 0.002mmHg at 25°C
Muuqashada Cadaan adag
Midabka Cad midab lahayn
BRN 5936353
pKa -1.71±0.20 (La saadaaliyay)
Xaalada Kaydinta 2-8°C
Tusmada Dib-u-celinta 1.481

Faahfaahinta Alaabta

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Khatarta iyo Badbaadada

Sharaxaada Badbaadada 24/25 - Ka fogow taabashada maqaarka iyo indhaha.
WGK Germany 3
Koodhka HS 29339900
Heerka khatarta QABOW

Macluumaadka Tixraaca

Hordhac n-tert-butoxycarbonyl-3-piperidone waa sunta cayayaanka muhiimka ah, sidoo kale waa dhex dhexaad u ah dhexdhexaadiyeyaasha farmashiyaha iyo kuwa kale ee kiimikada ah. Waxaa jira noocyo kala duwan oo hababka synthetic ee jira: (1) iyadoo la isticmaalayo γ-butyrolactone sida alaabta ceeriin, ka dib benzylaminolysis, hydrolysis, esterification, uumi leh ethyl bromoacetate, baaskiil, falcelinta lix-tallaabo ee hydrolytic decarboxylation soo saartaa 1-benzyl-3-piperidone hydrochloride, oo ay ku xigto debenzylation ee kooxda tert-butoxycarbonyl si loo bixiyo n-tert-butoxycarbonyl-3-piperidone (US0053565). (2) oo leh 3-hydroxypyridine sida walxo ceeriin ah, falcelin leh benzyl bromide si loo soo saaro milix ammonium quaternary, hoos u dhigista sodium borohydride, Palladium carbon debenzyl on tert-butoxycarbonyl, N-tert-butoxycarbonyl-3-piperidone (CN103204801) ayaa lagu helay hoos-u- oksaydhka heerkulka dimethyl sulfoxide.
Codsiga n-tert-butoxycarbonyl-3-piperidone waa mid dhexdhexaad ah oo ka mid ah isku-darka organic iyo dhexdhexaadinta daawada, waxaa loo isticmaali karaa cilmi-baarista shaybaarka iyo habka horumarinta iyo habka isku-darka daawada kiimikada, oo inta badan loo isticmaalo isku-dhafka xakamaynta stereo ee xeryahooda chiral.
Isticmaal N-tert-butoxycarbonyl-3-piperidone waxaa loo isticmaalaa isku-dhafka stereologically la xakameeyey ee xeryahooda chiral.

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